Projects

March 12, 2024

Taking Radioligand Therapy on the Road

Taking Radioligand Therapy on the Road

Zereau

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This is the innovative concept behind InHealth’s relocatable Radioligand Therapy (RLT) service: a purpose-built treatment facility designed to bring advanced nuclear medicine therapies closer to patients across the United Kingdom.

How InHealth’s pioneering relocatable therapy facility uses Zereau’s Toilet Filter System to bring advanced cancer treatment closer to patients.

And inside this remarkable facility is a Zereau Toilet Filter System (TFS), demonstrating how compact, source-based wastewater filtration can support entirely new approaches to delivering cancer care.

“What if radioligand therapy could come closer to the patient, rather than the patient having to travel to a specialised hospital?”

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Bringing treatment closer to patients

Radioligand therapy is transforming cancer treatment, currently particularly for patients with certain neuroendocrine tumours and advanced prostate cancer. However, access to these therapies remains limited. Treatment requires specialised facilities, trained personnel, radiation protection measures and appropriate infrastructure for managing radioactive waste.

Traditionally, this infrastructure is concentrated in relatively few specialised hospitals, requiring patients to travel considerable distances for treatment. InHealth recognised an opportunity to change this model.

In January 2024, the company announced the development of the world’s first relocatable radioligand therapy facility. Rather than relying exclusively on permanent hospital infrastructure, the facility can be relocated to different healthcare locations, supporting existing services or helping establish new treatment pathways.

The concept combines patient-focused treatment areas, specialist radiopharmaceutical preparation facilities and the necessary radiation protection measures within a single relocatable unit.

It is an innovative approach to expanding treatment capacity while improving geographical accessibility.

Still needed: InHealth’s relocatable radioligand therapy facility, on site.
Still needed: InHealth’s relocatable radioligand therapy facility, on site.

The wastewater challenge of mobile nuclear medicine

Delivering radioligand therapy outside a conventional hospital environment presents a particular engineering challenge. Following treatment, patients excrete part of the administered radioactivity, primarily through urine.

In conventional nuclear medicine departments, radioactive wastewater is frequently collected in dedicated decay tanks, where it is stored until radioactivity has decreased sufficiently to permit discharge.

These installations can require substantial space, complex piping, radiation shielding and significant construction work. For a relocatable treatment facility, a conventional decay tank infrastructure would obviously not work. A mobile facility needs compact, reliable systems that can operate within a restricted footprint.

“This is where Zereau’s source-based filtration offered a different approach.”

Source

A complete toilet and filtration system in one compact solution

InHealth’s relocatable RLT facility incorporates Zereau’s RadiCatch Toilet Filter System. The TFS is a patient toilet with an integrated filtration system designed to capture radionuclides from urine directly at the source. Radionuclides are retained in dedicated replaceable filters. The system is designed to achieve very high radionuclide removal efficiencies, with performance depending on the radionuclide and operating conditions. Its compact, all-in-one configuration makes it particularly suitable for applications where space is limited and conventional wastewater infrastructure is impractical. Only filters need to be stored for decay at the hospital’s premises, when the truck is relocated.

Enabling a new model of cancer care

The collaboration illustrates a broader opportunity for nuclear medicine. As radioligand therapies become more widely available, healthcare providers are searchnig for solutions to expand capacity. Infrastructural consequences to start or expand are challenging and expensive. Relocatable solutions can then support such expansion plans.

The InHealth facility demonstrates that specialised radioactive wastewater management can be integrated into a compact, relocatable treatment environment. This creates opportunities beyond traditional hospital departments, including satellite treatment facilities, temporary capacity extensions and new regional treatment services.

Innovation through integration

What makes the InHealth project particularly interesting is not simply that it incorporates advanced technology. It is the way several technologies have been brought together to create an entirely new healthcare delivery model.

Specialist radiopharmaceutical handling, patient treatment facilities, radiation protection and wastewater management have all been integrated into a relocatable unit. The Zereau Toilet Filter System forms one important part of this integrated solution. For Zereau, the project is an excellent example of how compact, source-based filtration can support innovation far beyond conventional hospital installations.

“Zereau is proud that its Toilet Filter System forms part of InHealth’s pioneering relocatable radioligand therapy facility.”

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